Question: Leber’s hereditary optic neuropathy (LHON) is a degenerative disease of the retina, caused by a m…



NonMendelian Inheritance – Genetics

Question: Leber's hereditary optic neuropathy (LHON) is a degenerative disease of the retina, caused by a m...

Show transcribed image text Leber's hereditary optic neuropathy (LHON) is a degenerative disease of the retina, caused by a mutation in a mitochondrial gene. If a woman and man, both of whom have LHON, mate what portion of their children do you expect to have LHON? If one of their daughters mates with a man who does not have LHON, what portion of her children do you expect to have LHON? If one of their sons mates with a woman who does not have LHON, what portion of his children do you expect to have LHON?

Leber's hereditary optic neuropathy (LHON) is a degenerative disease of the retina, caused by a mutation in a mitochondrial gene. If a woman and man, both of whom have LHON, mate what portion of their children do you expect to have LHON? If one of their daughters mates with a man who does not have LHON, what portion of her children do you expect to have LHON? If one of their sons mates with a woman who does not have LHON, what portion of his children do you expect to have LHON?

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