Question: The retinoblastoma gene (rb) encodes a protein that inhibits E2F, a transcription factor that act…
Show transcribed image text The retinoblastoma gene (rb) encodes a protein that inhibits E2F, a transcription factor that activates several genes involved in cell division. Mutations in rb are associated with certain forms of cancer. Under the following conditions would you expect cancer to occur? Both copies of rb are functional, one ropy of E2F in defective a. no One copy of rb is defective, both copiei of E2F in functional b. yes Both copies of rb are defective, both copies of E2F are functional. Both copies of rb are defective, one copy of E2F is defective. Both copies of rb and E2F are defective.
The retinoblastoma gene (rb) encodes a protein that inhibits E2F, a transcription factor that activates several genes involved in cell division. Mutations in rb are associated with certain forms of cancer. Under the following conditions would you expect cancer to occur? Both copies of rb are functional, one ropy of E2F in defective a. no One copy of rb is defective, both copiei of E2F in functional b. yes Both copies of rb are defective, both copies of E2F are functional. Both copies of rb are defective, one copy of E2F is defective. Both copies of rb and E2F are defective.
