Question: 1. What type of point mutation would depurination cause?
a. Deletion
b. Insertion
c. A deletion o…
1. What type of point mutation would depurination cause?
a. Deletion
b. Insertion
c. A deletion or an insertion
d. Transition e. Transversion
f. A transition or a transversion
Questions 2 -4 are based on the following information: The
sequence below corresponds to the first 15 bases of the coding
strand for a gene in E. coli . DNA base sequence (coding strand):
5’ – ATG GGC CTA ATC AAA … A mutated sequence has been found: 5’ –
ATG GGC CTA ATC AGA …
2. What mutation has occurred at the DNA level?
a. Transposition
b. Transition
c. Transversion
d. Insertion
e. Transmutation
3. What mutation has occurred at the protein level?
a. Frameshift
b. Missense
c. Neutral
d. Nonsense
e. Silent
4. The mutation above would probably
a. affect protein function because it is near the beginning of
the protein’s amino acid sequence.
b. not affect protein function because it is near the beginning
of the amino acid sequence, but it would affect function if it were
to occur in the middle or near the end of the protein’s amino acid
sequence.
c. not affect protein function.
5. Which term is used to describe enzymes that are always
produced, regardless of environmental conditions?
a. inducible
b. negatively controlled
c. constitutive
d. repressible
e. cis-acting
Consider positive control
in a repressible operon.
6. The regulator protein a(an) _________________________ .
(active activator, active
repressor, inactive activator, inactive repressor)
7. The effector is a(an) _________________________ .
(activator, co-repressor, inducer,
inhibitor, repressor)
8. Which of the following operons will produce functional
β-galactosidase if lactose is absent?
a. lacI + lacP +
lacOC lacZ –
b. lacI + lacP + lacO
+ lacZ +
c. lacI – lacP
– lacOC lacZ
+
d. lacI – lacP
+ lacO+ lacZ +
e. lacI +
lacO+ lacZ +/
lacOC
f. none of the above
g. all of the above
