Question: Which of the following forms of mutagenesis is not appropriate
for a forward genetics experiment?…



Which of the following forms of mutagenesis is not appropriate
for a forward genetics experiment?

a) Ionizing radiation such as X-rays

b) Creating a chimeric reporter gene to determine where in the
organism a candidate regulatory sequence drives expression.

c) Using transposons

d) Chemical EMS mutagenesis

In the course of evolution, the most common source of new genes
in eukaryotes has been?

a) Robertsonian translocation

b) DNA duplication

c) Alternative splicing

d) Reverse translation

e) Whole genome duplication

Genes that have a common ancestor and have split due to
speciation event are known as

a) Homologues

b) Orthologues

c) Paralogues

d) Monologues

Luria and Delbruck’s experiment showed that mutations are
directed.

a) True

b) False

An indel in a protein-coding region may result in a frameshift
mutation.

a) True

b) False

Mutations occurring within introns will not affect the structure
of the protein.

a) True

b) False

F+, F’, and Hfr bacteria can only conjugate with F-
bacteria.

a) True

b) False

Transduction alters a bacterial genotype only if homologous
recombination occurs.

a) True

b) False

Only eukaryotes have operons.

a) True

b) False

Histone modifications affect chromatin structure and can be
epigenetically inherited.

a) True

b) False

While most regulation of gene expression occurs through the
control of translation, RNA silencing regulates expression during
transcription.

a) True

b) False

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