Question: The citric acid cycle is a major hub of metabolism. How is the citric acid cycle regulated? Wha…
Show transcribed image text The citric acid cycle is a major hub of metabolism. How is the citric acid cycle regulated? What metabolites serve as starting points for the metabolic pathways of fats and proteins? Recent research implicates mis-regulation of the citric acid cycle and development of certain cancers. Do some further reading and write a short paragraph on the topic of hypoxia. Review your textbook (p. 515) on the regulation of hypoxia in cancer cells. Propose a new cancer drug and biochemical target based on this information.
The citric acid cycle is a major hub of metabolism. How is the citric acid cycle regulated? What metabolites serve as starting points for the metabolic pathways of fats and proteins? Recent research implicates mis-regulation of the citric acid cycle and development of certain cancers. Do some further reading and write a short paragraph on the topic of hypoxia. Review your textbook (p. 515) on the regulation of hypoxia in cancer cells. Propose a new cancer drug and biochemical target based on this information.
