Question: 11.
Which of the following is NOT an example of epigenetics?
Genomic imprinting
Paramu…
| 11. |
Which of the following is NOT an example of epigenetics? |
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Genomic imprinting |
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Paramutation |
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Independent assortment of alleles |
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X inactivation |
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Creation of iPSCs
| 12. |
(Problem 17) Define genomic imprinting. |
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Genomic imprinting is the differential expression of a gene
that depends on the sex of the parent that transmitted the
gene. |
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Genomic imprinting is the regulation of expression of a gene
where expression of both copies in a diploid cell may be equally
reduced through epigenetic silencing. |
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Genomic imprinting occurs when one X chromosome in each cell is
randomly inactivated to provide equal expression of X-linked genes
in males and females. |
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Genomic imprinting occurs when one copy of certain genes in
each cell is randomly inactivated during embryo development. |
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Genomic imprinting is observed in mammals when a male imprints
on a female and they become mating partners for life. |
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| 13. |
A group of scientists is studying memory in mice. They feed
sodium butyrate, a histone deacetylase inhibitor, to a group of
older mice and then subject them to memory exercises. How do you
predict the memory of treated mice might compare with the memory of
untreated mice? |
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Histone acetylation decreases with age, so sodium butyrate may
impair memory in older mice. |
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Histone acetylation is not associated with memory in mice. |
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Histone acetylation increases with age, so sodium butyrate may
impair memory in older mice. |
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Histone acetylation increases with age, so sodium butyrate may
improve memory in older mice. |
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Histone acetylation decreases with age, so sodium butyrate may
improve memory in older mice. |
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| 14. |
In mammals, what nucleotide would you expect to immediately
follow a methylated cytosine? |
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Adenine |
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Thymine |
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Cytosine |
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Guanine |
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Any nucleotide |
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| 15. |
___________ is a property of cells that allows them to develop
into any type of cell in an organism. |
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Epigenetic potential |
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Transcription |
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Pluripotency |
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Terminal differentiation |
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Reprogramming |
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| 16. |
What do you expect would develop if you injected Dnmt3
siRNA into honeybee larvae? |
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Female worker or queen |
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Male drone |
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Male drone or female worker |
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Female queen |
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Female worker |
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| 17. |
What epigenetic marks occur during X inactivation? |
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H3K27 acetylation |
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H3S10 phosphorylation |
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H3K79 methylation |
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H2B ubiquitylation |
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H3K27 methylation |
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| 18. |
(Problem 24) Which honeybee in Figure 21.4 (the
worker or the queen) will have more copies of 5-methylcytosine in
their DNA? Explain your answer.
WILDLIFE GmbH/Alamy.
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The worker. The bee that develops into the queen is fed royal
jelly, which promotes the expression of the Dnmt3 gene,
leading to lower DNA methylation. |
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The queen. The bee that develops into the queen is fed royal
jelly, which promotes the expression of the Dnmt3 gene,
leading to higher DNA methylation. |
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The worker and the queen have similar copies of
5-methylcytosine in their DNA because queen development depends on
histone acetylation rather than DNA methylation. |
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The queen. The bee that develops into the queen is fed royal
jelly, which inhibits the expression of the Dnmt3 gene,
leading to higher DNA methylation. |
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The worker. The bee that develops into the queen is fed royal
jelly, which inhibits the expression of the Dnmt3 gene,
leading to lower DNA methylation. |
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| 19. |
________ cells are undifferentiated cells that are capable of
forming every type of cell in an organism. |
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Stem |
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Somatic |
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Germ |
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Liver |
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Cancer |
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| 20. |
(Problem 4, part 1) Which of the following is the major form of
DNA methylation that is seen in eukaryotes? |
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5-methylcytosine |
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5-methylthymine |
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3-methyladenine |
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7-methylguanine |
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3-methyluracil
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