Question: Mapping Circular Chromosomes
4 different Hfr strains of E. coli are known to
transfer their genet…
Mapping Circular Chromosomes
4 different Hfr strains of E. coli are known to
transfer their genetic material during conjugation in different
sequences. Given the time of entry of the marker genes into the
F– recipient cell, construct a circular genetic map
which contains all these genes and label the time distance between
adjacent genes.
| Strain #1 | Gene: | arg – thy – met – thr |
| Time (min): | 15 21 32 48 | |
| Strain #2 | Gene: | mal – met – thi – thr – try |
| Time (min): | 10 17 22 33 57 | |
| Strain #3 | Gene: | phe – his – bio – azi – thr – thi |
| Time (min): | 6 11 33 48 49 60 | |
| Strain #4 | Gene: | his – phe – arg – mal |
| Time (min): | 18 23 35 45 |
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