Question: In the MAPK system what do you find to be the most sensitive and
least sensitive parameters? Expl…



In the MAPK system what do you find to be the most sensitive and
least sensitive parameters? Explain, in terms of the equations,
concentrations and rate constants in the model why you think the
model is sensitive/insensitive to those two parameters. Parameters:
Receptor concentration, extracellular growth factor concentration,
Grb2/SOS, Ras, kinases Raf (MAPKKK), MEK (MAPKK) and ERK
(MAPK).

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