BEDFORD BLEOMYCIN FOR INJECTION USP BLE-POS LATO Chrono Rx ONLY To reduce the development of restant bacteria and maintain th

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BEDFORD BLEOMYCIN FOR INJECTION USP BLE-POS LATO Chrono Rx ONLY To reduce the development of restant bacteria and maintain the effectiveness of any and other antibacterul dngn, bleomycin should be used only to treat or prevent infections that are prown or strongly suspected to be caused by bacteria WARNING It is recommended that thomycin be administered under the supervision of a qualified physician erenced in the use of cancer chemotherapeute agents. Appropriate management of therapy and complication is possible only when adequate diagnostic and treatment facilities werday w Pulmonary fibrosis is the most see toxicity associated with bloomycin. The most frequent presentation is premontis occasionally progressing to pulmonary libros. Its currence is higher the patients and in those moving than 400 units totaldos, but pulmonary forced been observed in young patients and those treated with low does. Asemn dosyncratic reaction consisting of hypotention, mental confusion, fever, chills, and wearing has been reported in approximately 15 cm phoma patients treated with bloomycin DOSAGE AND ADMINISTRATION Because of the posibility of anaphyladold reaction plana patients should be treated with 2 units ar tous for the first two to. Il no seutu actions, then the regular dos peschedule may be followed The following dose schedule is recommended Squamour coll carcinoma, non-Hodgkin’s lymphoma testleulat carcinoma-029 to 0.50 untsig (10 to 20 untum!) ghen intravenony, Intranet bairty, or subcutaneously way or twice weeky Hodgkin’s Disease 25 to 0.50 unitsig (10 to 20 unitsgiven intravenously, intramuscularly or suby way or twowy, Antara 50% response, a maintenance dose of 1 unit daily or 5 units woskytnously or intramuscularly should be given Pulmonary tandcity of bloomycin appears to be dose related with a string increase when the total de sower 400 units. Totaldoses over 400 unit should be given with great caution Mo: Wholen for action in combination with other throplate agents, proces may lowed Ingrowers of Hodgkin’s Dress and sticular tumors prompt and noted thin 2 was foi promet in by itim,mprovint un Squamous cel care respond more slowly, sometimes requiring as long as well for any improvement is ded, Malignant Powston-60 units administered as a single dose bohus intraplural injection (Administration Intrapleural). Uw with Bedford Lates. A din Bebe AS 14. A woman weighing 114 pounds who stands 63 inches tall is suffering from Hodgkin’s Disease. Calculate her recommended dosage range of Bleomycin. 15. The order is for 0.5 mg of a drug with dosage strength 200 mcg per 1.5 ml. a. Calculate the mL dosage using the ratio/proportion method, showing all steps. b. Calculate the ml dosage using the dimensional analysis method, showing all steps. c. Calculate the mL dosage using the formula method, showing all steps.
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