Question: Certain microorganisms that have a modified citric acid cycle, decarboxylate a-ketogluterate to p…
Show transcribed image text Certain microorganisms that have a modified citric acid cycle, decarboxylate a-ketogluterate to produce succinate semialdehyde (strucure below) instead of succinate CoA. Succinate semialdehyde is then converted to succinate, which is further metabolized by standard citric acid cycle enzymes. What kind of reaction is required to convert succinate semialdehyde to succinate? Draw a balanced reaction and show any coenzyme that might be required. Based on your answer to question 2(a), how does this pathway (the modified on e with no succinate Co-A intermediate) compare to the standard citric acid cycle energy yield (that is what are the products of this modified cycle that ultimately generate ATP compared to these products from the normal cycle).
Certain microorganisms that have a modified citric acid cycle, decarboxylate a-ketogluterate to produce succinate semialdehyde (strucure below) instead of succinate CoA. Succinate semialdehyde is then converted to succinate, which is further metabolized by standard citric acid cycle enzymes. What kind of reaction is required to convert succinate semialdehyde to succinate? Draw a balanced reaction and show any coenzyme that might be required. Based on your answer to question 2(a), how does this pathway (the modified on e with no succinate Co-A intermediate) compare to the standard citric acid cycle energy yield (that is what are the products of this modified cycle that ultimately generate ATP compared to these products from the normal cycle).
