Question: When the level of glucose in
the environment is low, abundant cyclic adenosine monophosphate
(cAM…
When the level of glucose in
the environment is low, abundant cyclic adenosine monophosphate
(cAMP) binds the catabolite activator protein (CAP) to form the
CAP-cAMP complex, which binds DNA. When CAP–cAMP binds DNA, the
efficiency of RNA polymerase binding is increased at the lac operon
promoter, which increases transcription of the structural genes.
However, when glucose levels are high, the CAP–cAMP complex does
not form and RNA polymerase cannot bind to the promoter
efficiently.
Show transcribed image text When the level of glucose in the environment is low, abundant cyclic adenosine monophosphate (CAMP) binds the catabolite activator protein (CAP) to form the CAP-cAMP complex, which binds DNA. When CAP-CAMP binds DNA, the efficiency of RNA polymerase binding is increased at the lac operon promoter, which increases transcription of the structural genes. However, when glucose levels are high, the CAP-CAMP complex does not form and RNA polymerasecannotbind to the promoter efficiently Low glucose RNA polymerise P, laci lacp aco lacZhcY loc High glucose RNA acO Is the lac operon inducible or repressible? O inducible cannot determine O repressible Continued below
When the level of glucose in the environment is low, abundant cyclic adenosine monophosphate (CAMP) binds the catabolite activator protein (CAP) to form the CAP-cAMP complex, which binds DNA. When CAP-CAMP binds DNA, the efficiency of RNA polymerase binding is increased at the lac operon promoter, which increases transcription of the structural genes. However, when glucose levels are high, the CAP-CAMP complex does not form and RNA polymerasecannotbind to the promoter efficiently Low glucose RNA polymerise P, laci lacp aco lacZhcY loc High glucose RNA acO Is the lac operon inducible or repressible? O inducible cannot determine O repressible Continued below
