Question: 4) Albinism is a skin pigmentation disease and is controlled by
a single gene. Albinism is a rece…
4) Albinism is a skin pigmentation disease and is controlled by
a single gene. Albinism is a recessive trait and the mutant form is
“a”. Consider a marriage between two normal individuals, both of
whom are known carriers (Aa).
a. If they have four children, what is the probability that all
four will be phenotypically
normal?
b. If they have four children, what is the probability that all
four will have only the wild-
type alleles (AA) and the trait will be lost in future
generations?
d. If they have four children, what is the probability that two
will be albino?
e. What is the probability that the father will produce an “a”
gamete?
f. What it the probability that the first child will be an
albino girl?
g. In a study on a large number of families in which both
parents are known to be carriers, a total of 138 normal and 22
albino children were observed. Do the numbers deviate significantly
from expected? Calculate the Chi square value, degrees of freedom,
and probability.
