Question: The hydrolysis of guanosine triphosphate (GTP) is given by the
following reaction:
GTP + H2O → GD…



The hydrolysis of guanosine triphosphate (GTP) is given by the
following reaction:

GTP + H2O → GDP + Pi

with Κ’ 298 = 1.9 x 105 . In a retinal cell, the concentrations
of these species are [GTP] = 50 mM, [GDP] = 5 mM, and [Pi] = 15 mM.
Calculate ∆Grxn in a retinal cell at 25o C. Will the reaction occur
spontaneously in the cell?

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