Question: Mammary epithelial cancer cells have amplified levels of EGF receptors on their surface. if such …

Mammary epithelial cancer cells have amplified levels
of EGF receptors on their surface. if such a cell has 1000 EGF
receptors, as compared to 200 receptors on a normal cell, what
minimum concentration of EGF is required to induce cell
proliferation in the cancer cell? [show calculation; note that the
same number of receptors (not percentage) must be activated to
promote proliferation in normal or cancer cells]
Kd = 1 × 10^-10 M
At least 25% of receptors on a normal cell must be engaged by EGF
in order to trigger the cellular proliferation response.