Question: 1. A transcription factor that recruits histone
acetyltransferase (HAT) will have what general ef…



1. A transcription factor that recruits histone
acetyltransferase (HAT) will have what general effect on genes?

A) Transform 10 nm chromatin fibers into 30 nm chromatin
fibers.
B) Remove positive charges from histones.
C) Convert euchromatin to heterochromatin.
D) Repress transcription.
E) Recruit chromodomain proteins.

2. Which of the following is not true
of bacterial helix-turn-helix proteins?

A) Can alter gene expression by chemical modification of
histones.
B) Consensus nucleotide sequence is an inverted repeat
(palindrome).
C) Bind to DNA with two identical subunits.
D) Sequence-specific DNA binding.
E) Recognition helix forms non-covalent bonds within the major
groove.

3. Which of the following is not true
of the yeast transcription factor GAL-4?

A) Displaces nucleosomes so that the RSC complex can bind
DNA.
B) Binds to DNA as a homodimer.
C) Normally activates transcription of the GAL1
gene.
D) Binds to a DNA sequence known as UAS.
E) Has physically separate DNA-binding and activation
domains.

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