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An antitubercula drag Rifampicin is given to Ms. Laurel Steplats (a 32-year-old woman weighing 50 Kg) in a dose of 35 mg kg/day in one single IV bolus injection. I Rifampicin has a plasma balf-life of 8 hours, 70% of the drug is metabolized in liver, and a volume of distribution is 0.85 L/Kg, what is the Hepatic cleacacice (CI)? 10 H
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