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An antitubercular drug, Rifampicin is given to Ms. Laurel Stephens (a 32-year-old woman weighing 50 Kg) to a dose of 35 mg kg day in one single IV bolus injection. If Rifampicin has a plasma half-life of 8 hours, 70% of the drug is metabolized in liver, and a volume of distribution is 0.85 L/Kg. What is the real clearance (1) 01-01
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