Question: 1 Pts Drug Responses Can Vary In The Elderly Because: O Reduced Kidney Function Can Cause An Accumulation Of Drug And Increase Risk Of An Adverse Response. Liver Enzymes Have Increased Activity Leading To Shorter Half Lives. They Have Increased Blood Flow (and Hence Distribution) Due To Reduced Elasticity Of Vessel Walls. O All Of The Above Are Correct. …

1 pts Drug responses can vary in the elderly because: O Reduced kidney function can cause an accumulation of drug and increase risk of an adverse response. Liver enzymes have increased activity leading to shorter half lives. They have increased blood flow (and hence distribution) due to reduced elasticity of vessel walls. O All of the above are correct. 1 pts Children have a relatively fast metabolism of drugs in comparison to adults. Why? O Humans are born with more liver enzymes and they gradually lose them as they age. Their liver is proportionately larger in comparison to the rest of their body. They acquire extra metabolic enzymes via breast milk which persist for many years. The statement is false – the immaturity of a child’s liver means it will not be able to metabolise drugs as well as adults. 1 pts Pregnant women may need to consult with their doctor regarding any medications because: O Some medications are teratogens. Some medications can cross the placenta. Some medications will be cleared at a faster rate due to increased GFR during pregnancy, O All of the above are correct.