Question: A New Drug Is To Be Given By Multiple IV Bolus Injections To A Patient Such That Drug Steady-state Concentrations Should Be Maintained Between A Maximum Of 20 And A Minimum Of 1 Mg/L. Assume A One Compartment Linear Model Applies To This Drug In This Concentration Range. The Elimination Rate Constant And Apparent Volume Of Distribution For This Drug …

A new drug is to be given by multiple IV bolusinjections to a patient such that drug steady-state concentrationsshould be maintained between a maximum of 20 and a minimum of 1mg/L. Assume a one compartment linear model applies to this drug inthis concentration range. The elimination rate constant andapparent volume of distribution for this drug in this patient are0.223 hr-1 and 40.6 L, respectively. Calculate the dosing intervalthat will exactly achieve this concentration requirement. Also,calculate the maintenance dose

2.

3.