1) The half-life and volume of distribution of an antibiotic are9.51 h and 21.63 L, respectively. A patient was given an IV bolusdose of 171.46 mg of this antibiotic. Please calculate the plasmadrug concentration 8.23 h after the IV injection.
2) Following an IV bolus dose of an anticoagulant, the plasmadrug concentration was measured as 5.72 mg/L, 1.4 mg/L, and 0.15mg/L at 1.00 h, 4.56 h, and 9.99 h post IV injection. Pleasecalculate the elimination rate constant, k, for thisanticoagulant.]
(Visited 3 times, 1 visits today)
Related posts:
- Question: An Antibiotic Was Infused With A 40-mg IV Dose Over 2 Hours. Ten Hours Later, A Second Dose Of 40 Mg Was Infused, Again Over 2 Hours. (a) What Is The Plasma Drug Concentration 2 Hours After The Start Of The First Infusion? (b) What Is The Plasma Drug Concentration 5 Hours After The Second Dose Infusion Was Started? Assume K = 0.2 Hr-?, V= 10 L For The …
- Question: Assume The Same Drug As Above (ie, K = 0.2 Hr“), Vp = 10 L) Was Given By Multi- Ple IV Bolus Injections And That At A Dose Of 100 Mg Every 6 Hours For 6 Doses. What Is The Plasma Drug Concentration 4 Hours After The 6th Dose, If The 5th Dose Were Given An Hour Late? Substitute Into Equation 8.26 For All Unknowns: K = 0.2 Hr“), V = 10 L, D = 100 …
- Question: Antibiotics Case Patient CS Is A 35-year-old Male Weight 76.6 Kg. The Patient Is To Be Given Multiple IV Bolus Injections Of An Antibiotic Every 6 Hours. The Effective Concentration Of This Drug Is 15 Ug/mk. After The Patient Is Given A Single IV Dose, The Elimination Half-life Is Determined To Be 3.0 Hours And The Apparent Volume Of Distribution If …
- Question: An Antitubercular Drug, Rifampicin Is Given To Ms. Laurel Stephens (a 32-year-old Woman Weighing 50 Kg) To A Dose Of 35 Mg Kg Day In One Single IV Bolus Injection. If Rifampicin Has A Plasma Half-life Of 8 Hours, 70% Of The Drug Is Metabolized In Liver, And A Volume Of Distribution Is 0.85 L/Kg. What Is The Real Clearance (1) 01-01
- Question: Drug A Is Low Concentration Of Nicotine Drug B Is Low Concentration Of Caffeine Drug C Is High Concentration Of Caffeine Drug D Is High Concentration Of Nicotine Drug E Is High Concentration Of Ethanol Please Make The Graph Digitally.
- Question: Homework: 1. 100 Mg Of Drug Is Given Orally Every 6 Hours To A 70 Kg Patient. The Bioavailable Fraction After Oral Dosing Is 50%. The Drug Has A Half Life Of 6 Hours. The Plasma Level Of The Drug When First Administered Is 1.02 Mg/liter. How Long Will It Take To Achieve A Plasma Concentration Of 0.51mg/liter.
- Question: In Phase-1 Clinical Trial, A New Antibiotic Is Being Tested In An Adult Person. The Antibiotic Has The Following Pharmacokinetic Parameters: Clearance = 100 L/hour, Vd 50 L, T½ = 3 Hours. If The Drug Has To Be Administered Intravenously, What Dose Should Be Given To Quickly Obtain A Plasma Concentration Of 10 Mg/L?
- Question: An Antitubercular Drug Rifampicin Is Given To Ms. Laurel Stephens ( 32 Year Old Woman Weighing 50 K In A Dose Of 35 Mg/kg/day In One Single IV Bolus Injection. If Ritempicin Luns A Platun Half-life Of 8 Hours, 70% Of The Deug Is Metabolized In Liver, And A Vohuse Of Distribution Is 0.59 L/Kg When Will Drug Concentration Reach 1 Met Time Required – H …
- Question: Time (hours) Drug Drug Concentration In Concentration In Plasma Jurine (ug/ml) (ug/ml) 0 1 120 350 2 100 240 4 4. 73 180 6 56 110 12 28 52 18 13 20 24 16 7 30 3 35 1.5 1 40 10.9 0.4 Question 12 1 Pts What Is The Area Under The Curve From Time 6 Hour To 12 Hour For The Plasma Data? 125 110 172 242 Question 13 1.5 Pts What Is The Concentration At Time …
- Question: 138.The Medical Assistant Should Count The Pulse For How Long To Be Most Accurate? A. 15 Seconds B. 30 Seconds C. 1 Minute D. 2 Minutes 129 Antibiotic Resistance Is Best Prevented By 2. Prescribe More Than One Antibiotic To The Patient. B. Prolong The Antibiotic Treatment. C. Follow The Recommended Dose And Duration Of The Antibiotic Treatment. D. Increase …
