Case of Steady-State Calculation:
A 68-year-old 85 kg male is hospitalized following an acutemyocardial infarction complicated by recurrent episodes ofventricular tachycardia. Treatment is initiated with an initial 85mg dose of intravenous lidocaine administered over 2 minutes.Estimated lidocaine distribution volume is 1.0 L/kg and eliminationhalf-life is estimated at 2 hours. What maintenance infusion rate(in mg/min) will provide a steady-state plasma lidocaine level of 5mcg/mL in this patient?
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