1. Dietary iodine deficiency causes endemic colloidgoiter. Explain the mechanism for the development of extremelylarge thyroid gland in this disorder.
2. Hypocalcemia is seen to develop in chronic pancreatitis. Explainwhy calcium levels decrease in this disease and identify type ofnecrosis is observed in the pancreas of patients with chronicpancreatitis.
3. Explain how stretching of stomach affects the stomach secretoryactivity.

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