Question: 1. Trans-acting factors can affect any gene on any chromosome in
the same nucleus that has a matc…



1. Trans-acting factors can affect any gene on any chromosome in
the same nucleus that has a matching binding site.

a) True

b) False

2. The TATA box is a promoter-proximal element

a) True

b) False

3. Leucine zippers are found in many transcription factors. The
leucine zipper ________

a) is part of the DNA binding domain of those transcription
factors

b) promotes the dimerization of transcription factors containing
leucine zippers

c) is not important for the function of transcription
factors

d) prevents the dimerization of transcription factors containing
leucine zippers

4. Pha-4 is not expressed in C.elegans adult pharyngeal
cells

a) True

b) False

5. Which of the following statements are true regarding control
of gene expression by Myc proteins

a) Myc is activated by mitogen stimulation and exposure to
growth factors

b) Myc-Max heterodimers activate transcription and promote
proliferation

c) Mad-Max heterodimers repress transcription

d) One model of how Myc-Mad-Max complexes regulate transcription
suggests that upon exposure to growth factors, Myc target genes are
activated indirectly by sequestration of Max away from Mad

e) all of the aabove are true

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