Question: 1. Which of the following events initiates activation of the alternative complement pathway? A. C…

1. Which of the following events initiates activation of the
alternative complement pathway?

A. C1q binding to microbial surface

B. Mannose-binding lectin (MBL) binding to a microbial
surface

C. Complement receptor 1 (CR1) binding to C3b

D. Factor 1 cleavage of C3

E. Spontaneous cleavage of C3 to C3b

2. Which one of the following statements about primary and
secondary antibody responses is not true?

A. Antibodies in the primary responses generally have lower
affinity for antigen than those produced in secondary responses

B. Secondary responses reach peak levels more quickly than
primary responses

C. Primary responses require higher concentrations of antigen
for initiation than secondary responses

D. Primary responses occur to all types of antigens, but
secondary respones mosty occur only to protein antigens

E. Primary responses are characterized by IgG antibodies,
whereas secondary responses are dominated by IgM antibodies