Question: 1)Draw a small polypeptide, illustrating peptide bonds. Show
where a protease would cleave it bas…



1)Draw a small polypeptide, illustrating peptide bonds. Show
where a protease would cleave it based on its type (amino-,
carboxy-, endo-, etc.)1)Distinguish between general acid/base and
specific acid/base reactions.

2)Explain how metal ions aid in enzymatic catalysis.

3)Why are transition state analogs good enzyme inhibitors?

4)Explain why kcat/Km is the best parameter for catalytic
efficiency in vivo.

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