Question: 9. What is the role of topoisomerase in transcription? 10. How does the eukaryotic RNA polymerase…

9. What is the role of topoisomerase in transcription?

10. How does the eukaryotic RNA polymerase II promoter compare
to that of the E. coli promoter.

11. Describe in general the evolutionary conservation between
the eukaryotic and prokaryotic RNA polymerases and promoters. Why
would they be so conserved after about 500 million years (according
to the fossil record)?