Question: A 16-month-old Female Is Brought To ER By Her Mother After Appearing Cyanotic And Lethargic. The Mother Reports The Infant Had Been 'cranky' Due To Teething And She Applied A Topical Anesthetic Agent Having Nitrate As The Active Ingredient To Her Gums. An Arterial Blood Gas (ABG) Is Ordered And A Characteristic Chocolate-brown Colored Blood Is Observed. ...

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A 16-month-old female is brought to ER by her mother after appearing cyanotic and lethargic. The mother reports the infant had been ‘cranky’ due to teething and she applied a topical anesthetic agent having nitrate as the active ingredient to her gums. An arterial blood gas (ABG) is ordered and a characteristic chocolate-brown colored blood is observed. A diagnosis of methemoglobinemia is made. Which of the following coenzymes is most likely to be associated with the reduction of methemoglobin? Biotin FADH2 NADH Pyridoxal phosphate Tetrahydrofolate

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