A physician ordered Prevacid 30 mg daily for a patient with anasogastric tube. Below is a part of the product information ofPrevacid. Explain how will you dispense and administer theprescribed drug.
PREVACID (lansoprazole) is supplied in delayed-release capsulesfor oral administration. The delayed-release capsules are availablein two dosage strengths: 15 mg and 30 mg of lansoprazole percapsule. Each delayed-release capsule contains enteric-coatedgranules consisting of 15 mg or 30 mg of lansoprazole.
Lansoprazole is a white to brownish-white odorless crystallinepowder, which melts with decomposition at approximately 166°C.Lansoprazole is freely soluble in dimethylformamide; soluble inmethanol; sparingly soluble in ethanol; slightly soluble in ethylacetate, dichloromethane, and acetonitrile; very slightly solublein ether, and practically insoluble in hexane and water.Lansoprazole is stable when exposed to light for up to two months.The rate of degradation of the compound in aqueous solutionincreases with decreasing pH. The degradation half-life of the drugsubstance in aqueous solution at 25°C is approximately 0.5 hour atpH 5.0 and approximately 18 hours at pH 7.0.
