A promising new drug for the treatment of Alzheimer’sdisease is under development. During the chronic bioassay in mice,5% of the female mice and 1% of the male mice that were receivingthe highest daily dose of the drug developed liver failure. Furtherinvestigation suggested that a metabolite of the drug formed inmouse liver was responsible. Discuss the pros and cons ofcontinuing with development of this drug for treatment of people.Be sure to state what other facts you would need to know to make aninformed decision.
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