Forthis?
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A therapeutic in saline solution is infused into a patient over a period of 60 minutes. The therapeutic is absorbed into tissue from the blood stream at a rate proportional to the concentration in the blood. After an initial period the plasma concentration of the therapeutic is constant. a. (10 Points) Write out two species balances for the therapeutic (T) one for the initial period and a simplified one for after the initial period? b. (20 points) The therapeutic is administered at a rate of 150 mL per minute at a 2.5 M concentration? Determine the molar flow rate of therapeutic into the tissue if the plasma concentration is 0.25 M. c. (5 Points) What is the proportionality constant (k) based on the stable plasma concentration (value and units)? d. (20 points) Assuming constant volume for the system, how long does it take for the plasma to reach the 0.25 M concentration? e. (5 points) Estimate the final tissue concentration of the therapeutic after the infusion.
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