Question: Answer the following four questions about supercoiling and
linking number:
a) What is the linking…



Answer the following four questions about supercoiling and
linking number:

a) What is the linking number,
Lk, for a relaxed, closed-circular DNA with 4830 base pairs? Enter
your answer as an integer.

b) What is Lk for negatively supercoiled 4830 bp DNA if it is
underwound by 3 complete turns?

c) How does Lk change when there is a break in one strand?

d) What is Lk for negatively supercoiled 4830 bp DNA after
treatment with one molecule of topoisomerase I?

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