Question: Answer the following four questions about supercoiling and
linking number:
a) What is the linking…
Answer the following four questions about supercoiling and
linking number:
a) What is the linking number,
Lk, for a relaxed, closed-circular DNA with 4830 base pairs? Enter
your answer as an integer.
b) What is Lk for negatively supercoiled 4830 bp DNA if it is
underwound by 3 complete turns?
c) How does Lk change when there is a break in one strand?
d) What is Lk for negatively supercoiled 4830 bp DNA after
treatment with one molecule of topoisomerase I?
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