Question: AS, A 57-year-old Woman, Presents To Her Physician With Complains Of Palpitations That Started Few Months Ago. She Stated That Previously It Occurs Intermittently But Since One Week Experiences Daily. She Has Also Had Difficulty In Swallowing Food For The Past 2 Months And Has Been Unable To Sleep For Past 4 Days. She Noticed That Her Hair Has Become …

AS, a 57-year-old woman, presents to her physician with complains of palpitations that started few months ago. She stated that previously it occurs intermittently but since one week experiences daily. She has also had difficulty in swallowing food for the past 2 months and has been unable to sleep for past 4 days. She noticed that her hair has become more fine and thinner in distribution recently and neck feels swollen. She currently takes Ramipril 5 mg daily, furosemide 80mg daily and warfarin 2 mg daily. Her primary care doctor has performed routine thyroid function tests and found to have hyperthyroidism. BP: 150/90 mmHg HR: 85beats/min Weight: 57kg INR 1.3 TSH 1. State the various therapeutic objectives in this patient. 2. State the various signs and symptoms which are suggestive of hyperthyroidism in the patient. 3. State the various pharmacotherapeutic alternatives available for this patient (with dosage regimen). 4. State the various therapeutic and toxicity monitoring parameters that needs to be performed in this patient. 5. Identify potential or actual drug-drug and drug-disease interactions and provide your recommendations to manage it. THYROID DISORDERS AS, a 57-year-old woman, presents to her physician with complains of palpitations that started few months ago. She stated that previously it occurs intermittently but since one week experiences daily. She has also had difficulty in swallowing food for the past 2 months and has been unable to sleep for past 4 days. She noticed that her hair has become more fine and thinner in distribution recently and neck feels swollen. She currently takes Ramipril 5 mg daily, furosemide 80mg daily and warfarin 2 mg daily. Her primary care doctor has performed routine thyroid function tests and found to have hyperthyroidism. BP: 150/90 mmHg HR: 85beats/min Weight: 57Kg INR 1.3 TSH<0.081U/L 1. State the various therapeutic objectives in this patient. 2. State the various signs and symptoms which are suggestive of hyperthyroidism in the patient. 3. State the various pharmacotherapeutic alternatives available for this patient (with dosage regimen). 4. State the various therapeutic and toxicity monitoring parameters that needs to be performed in this patient. 5. Identify potential or actual drug -drug and drug-disease interactions and provide your recommendations to manage it.