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CASE STUDY #2 clinical Chemistry Rob G., a 60-year-old man came into the ER complaining of fatigue and overall flu-like symptoms. He was mildly jaundiced with icteric sclera. His liver profile and CBC results are shown below: 2/15 2/22 REFERENCE RANGE T. BILIRUBIN 2.2 1.9 0.2-1.2 mg/dL D. BILIRUBIN 1.19 NT 0.00-0.40 mg/dl AST 735 5.40 10/L ALT 373 NT 5-40 10/L ALK, PHOS 202 NT 30-157 IU/L ALBUMIN 2.1 1.9 3.5-5.0 g/dL T. PROTEIN 7.4 7.4 6.0-8.4 g/dL AMMONIA 32 48 20-80 ug/dL NTNot Tested 564 WBC RBC HBG HCT MCV MCH MCHC PLATELETS NEUTROPHILS LYMPHOCYTES MONOCYTES EOSINOPHILS BASOPHILS RBC MORPHOLOGY Rob G. 2.1 4.10 13.8 39 97 33 35 42 69 16 10 4 1 NORMAL REFERENCE RANGE 5-10 X 10/L 5-6 X 10/L 13.5-17.5 g/dL 41-53% 80-100 fL 26-34 pg 31-37% 150-400 x 10°/L 25-60% 20-50% 2-11% 0-8% 0-29 NORMAL Each question is worth one point. Please answer in full sentences, unless otherwise specified. Neatness counts. Answers must be legible or no credit will be given. Feel free to type the answers. 1. List the abnormal results. 2. What organ system is involved? 3. List 6 possible explanations for the chemistry results. 4. What is the most likely explanation for these results? HEPATITIS PROFILE IgM anti-HAV HBsAg IgM anti-HBC Anti-HCV Rob G. Nonreactive Nonreactive Nonreactive Reactive REFERENCE RANGE Nonreactive Nonreactive Nonreactive Nonreactive 5. What is the most likely diagnosis for this patient? 6. List five causes of this infection. 7. How could the physician differentiate between acute and chronic forms of this infection?
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