Question: Consider a study in which you capture 3000 wild male Drosophila melanogaster (each of which have …

Consider a study in which you capture 3000 wild male Drosophila
melanogaster (each of which have normal wings but unknown
genotypes) and mate each with laboratory females homozygous for the
autosomal recessive allele vg (vestigial, which causes miniature
wings when homozygous), and examine each male’s offspring. You find
that half of the offspring of each of three males have miniature
wings and have genotype vgvg. Why are these data inadequate to
estimate the rate of mutation from the wild type to the vg allele?
Assuming that you can accurately genotype adult flies, design a
mating study that would allow you to estimate mutation rates at
this locus.