Question: Human ABO blood groups are controlled by a single gene with
three alleles IA, IB, and i. The thre…



Human ABO blood groups are controlled by a single gene with
three alleles IA, IB, and i. The three alleles contribute to four
blood group phenotypes. In addition to the ABO blood groups, there
are two other loci that control blood phenotypes, the MN blood
group locus and the Rh factor locus. The MN blood group has two
codominant alleles, LM and LN. The Rh factor locus also has two
alleles, Rh and Rh-, where Rh is dominant. The two phenotypes at
the Rh+ factor locus are Rh+ and Rh-. Suppose in a population, the
frequency of the ABO allele IA is 0.36, and the IB allele frequency
is 0.26. In the same population, the frequency of the LM allele is
0.47, and the frequency of the Rh is 0.62. What is the frequency of
the genotype I^B i L^M L^N Rh+ Rh+ if the population is in
Hardy–Weinberg equilibrium?

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