Question: It takes approximately 3 protons flowing through ATP synthase to
generate one ATP. The oxidation …
It takes approximately 3 protons flowing through ATP synthase to
generate one ATP. The oxidation of one NADH results in 10 protons
being pumped across the inner membrane, yet the net ATP synthesis
for one NADH is 2.5 (as opposed to 3.33 ATP). What additional
reaction accounts for this discrepancy? In other words, what
happens to the protons which don’t pass through the ATP
synthase?
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