Question: James T., A 55-year-old Man, Visited His Physician Because He Noticed Abdominal Swelling And Complained Of Fatigue And Weakness. Upon Physical Examination, The Physician Noted Icteric Sclera.. Some Edema Around The Ankles, Splenomegaly, And Hepatomegaly. James Also Admitted To Drinking At Least 5 Martinis Every Night And More On Weekends For A Number …

James T., a 55-year-old man, visited his physician because he noticed abdominal swelling and complained of fatigue and weakness. Upon physical examination, the physician noted icteric sclera.. some edema around the ankles, splenomegaly, and hepatomegaly. James also admitted to drinking at least 5 martinis every night and more on weekends for a number of years. The following tests were ordered: Analyte James T. Reference Range Bilirubin, total Bilirubin, direct AST (ALP ALT Albumin GGT Total protein Cholesterol 2.5 mg/dL 1.51 mg/dly 350 IU/L 214 IU/L 200 IU/L 3.0 g/dl suht low 300 IU/L 7.2g/dL 160 mg/dL -0.2 – 1.2 mg/dL 0.0 -0.4 mg/dL 5 – 40 IU/L 30 – 157 IU/L 5 – 40 IU/L 3.5-5.0 g/dL 2-30 IU/L 6.0 -8.4 g/dL <200 mg/dL Prothrombin time 16 seconds 11 – 14 seconds Anti-HCV Anti-HAV (IgM) Anti-HAV (total) Anti-HBsAg Anti-HBcAg Nonreactive Nonreactive Nonreactive Nonreactive Nonreactive Nonreactive Nonreactive Nonreactive Nonreactive Nonreactive QUESTIONS Homo due to destructs o QBC 4. List 5 etiologies (causes) of this condition. RBCs causes ned generation of bilirubin 5. Given the results of James’s physical examination, history, and laboratory tests, what etiology is the most probable cause of this disease? Heavy alcohol use he use of dreniging of Martinis every night and more on weekends 6. Explain why the prothrombin time is prolonged and the albumin is decreased. 7. What is the cause of the abdominal swelling? **Case Studies in Clinical Laboratory Science 1s Edition, Linda Graves Ed.D MT (ASCP) and Elizabeth Gockel-Blessing, Prentice Hall.