Question: Li-Fraumeni syndrome is inherited in much the same fashion as familial retinoblastoma. It is caus…
Show transcribed image text Li-Fraumeni syndrome is inherited in much the same fashion as familial retinoblastoma. It is caused by mutation in the p53 gene, a tumor suppressor gene. For each question, there is more than one correct answer Which of the following genotypes is likely to be found in cells isolated from malignant tissue from a person with Li-Fraumeni syndrome? Which of the following genotypes is likely to be found in normal cells isolated from the same individual? Which of the following genotypes is likely to be found in normal cells of unrelated individuals not suffering from Li-Fraumeni syndrome? Which of the following genotypes is likely to be found in tumor cells of unrelated individuals not suffering from Li-Fraumeni syndrome? p53+/p53+ p53+/p53-p53-/p53-p53-/deleted p53-p53+/deleted p53-
Li-Fraumeni syndrome is inherited in much the same fashion as familial retinoblastoma. It is caused by mutation in the p53 gene, a tumor suppressor gene. For each question, there is more than one correct answer Which of the following genotypes is likely to be found in cells isolated from malignant tissue from a person with Li-Fraumeni syndrome? Which of the following genotypes is likely to be found in normal cells isolated from the same individual? Which of the following genotypes is likely to be found in normal cells of unrelated individuals not suffering from Li-Fraumeni syndrome? Which of the following genotypes is likely to be found in tumor cells of unrelated individuals not suffering from Li-Fraumeni syndrome? p53+/p53+ p53+/p53-p53-/p53-p53-/deleted p53-p53+/deleted p53-
