Question: Patients with familial retinoblastoma carry a germline mutation in
one copy of the Rb gene. Poten…
Patients with familial retinoblastoma carry a germline mutation in
one copy of the Rb gene. Potential mechanisms for inactivation of
the other allele in a retinoblastoma tumor arising in one of these
patients include: A an independent point mutation B loss of the
normal chromosome 13 C Mitotic crossing over D all of the above E
none of the above F A & C
one copy of the Rb gene. Potential mechanisms for inactivation of
the other allele in a retinoblastoma tumor arising in one of these
patients include: A an independent point mutation B loss of the
normal chromosome 13 C Mitotic crossing over D all of the above E
none of the above F A & C
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