Question: Pax6 as a transcription factor controls the expression of genes needed for both eye and pancreas …

Pax6 as a transcription factor controls the expression of genes
needed for both eye and pancreas function. So, how is it possible
for Pax6 to induce expression of the eye-specific genes in the eye,
but not in the pancreas? Explain the important concept of
combinatorial regulation involved in this process. Crystallin is
one of the eye-specific genes, whereas somatostatin is only
transcribed in pancreatic cells.