R.J,a 45-year-old, 100 kg, obese male (5’10”), is receivingtobramycin and piperacillin for pneumonia. R.J. does not have anythird spacing of fluid and a SrCr is 1.4 mg/dL. Calculate atobramycin dosing regimen that should achieve peak concentrationsof 6-8 mg/L and trough concentrations of <2mg/L.
Please show the steps.
Question is not incomplete. I make it up to the dose equation(bolus due to >3hr for half life) and am unsure what to use forCpss.
(Visited 4 times, 1 visits today)
Related posts:
- Question: A Peak And Trough Level Was Obtained From A Client Receiving An Aminoglycoside Iv Piggy Back Every 8 Hours. Which Finding Presents The Highest Risk For The Patient A. Decreased Peak Only B. Decreased Trough Only C. Increased Trough And Peak D. Decreased Peak And Trough
- Question: R.J. Was Started On Tobramycin 140 Mg IV Over 30 Mins Every 8 Hr. A Trough Tobramycin Level Of 1.5 Mg/L Was Taken Before The Start Of The Fourth Dose And A Subsequent Peak Level Was Obtained As 3 Mg/L, 30 Mins After The End Of The Half-hour Infusion. What Are The Revised PK Parameters For R.J. And Are The Revised Parameters Reasonable?
- Question: If A Drug Is Dosed Once Every 2 Half-lives, The Peak To Trough Ratio Will Be Approximately 4:1. Answers A – B A True B False Total Concentrations At Steady State Can Be Used To Determine What Is Happening With Free Concentrations At Steady State As Long As The Plasma Protein Binding Has Not Changed Answers A-B A True Fale
- Question: Select All The Antibiotics That Require Peak And Trough Dosing. (see Ppt Notes Tobramycin IV Gentamicin IV Vancomycin Metronidazole (Flagyl)
- Question: Jane Doe , A 40-year-old, 60 Kg, Non-obese Female With A SrCr Of 1 Mg/dL, Is Started On Gentamicin 300 Mg Infused Over One Hour Daily. Calculate The Expected Steady-state Peak Concentration At The End Of The One-hour Infusion, At 12 Hours After Starting The Infusion, And At The Trough. Please Show The Steps
- Question: T.I Is A 41-year-old, Who Weighs 70 Kg, Male, With An SrCr Of 1 Mg/dL, Was Prescribed Gentamicin 140 Mg IV Every 8 Hours. After Steady State Had Been Achieved, A Trough Concentration Of 0.7 Mg/L Was Obtained Just Before A Dose, And A Peak Level Of 4 Mg/L Was Obtained Two Hours After The End Of The Infusion, Which Lasted For 30 Minutes. Does T.I.’s Dose …
- Question: Question 3 1 Pts What Statement Made By The Nursing Student Regarding Half-life Is Correct? O “A Drug With A Short Half-life Takes A Long Time To Be Eliminated From The Body.” O “A Drug With A Long Half-life Has Active Drug Available For A Long Period Of Time In The Body.” “It Is The Amount Of Time It Takes For One And One-half Of The Strength Of A …
- Question: 12. A Patient Is To Receive Ampicillin 250 Mg IM Injection For Post-partum Infection. The Medication On Oand Reads 1 G/mL. How Many ML Will The Nurse Give? 13. The Physician Orders IV Tobramycin 12 Mg Every 12 Hours. The Pharmacy Sends The Following Vial Of Tobramycin. How Many ML Will The Nurse Give? NDC 63323-305-02 300502 TOBRAMYCIN INJECTION, USP …
- Question: Order: Tobramycin 8mg IM Q6 H For An Infant Who Weighs 5000g. The Recommended Dose Is 2-2.5mg/kg 9 8 H Or 1.5-1.9 Mg/kg Q6 H. NDC 63323-305-02 300502 TOBRAMYCIN INJECTION, USP PEDIATRIC 20 Mg Per 2 ML (10 Mg Per ML) For IM Or IV Use Must Dilute For IV Use. Rx Only 2 ML Multiple Dose Vial Each Ml Contains Tobramycin Sulfate Equivalent To 10 Mg To Bramycin; …
- Question: Homework: 1. 100 Mg Of Drug Is Given Orally Every 6 Hours To A 70 Kg Patient. The Bioavailable Fraction After Oral Dosing Is 50%. The Drug Has A Half Life Of 6 Hours. The Plasma Level Of The Drug When First Administered Is 1.02 Mg/liter. How Long Will It Take To Achieve A Plasma Concentration Of 0.51mg/liter.
