Question: Somatic Cell Hybridization
3 mouse-human hybrid cell lines retained specific human
chromosomes af…
Somatic Cell Hybridization
3 mouse-human hybrid cell lines retained specific human
chromosomes after many generations as shown in this data.
Human Chromosomes | |
X 3 5 7 9 17 20 21 | |
Cell Line | |
A | + + + + 0 0 0 0 |
B | 0 + 0 + 0 + 0 + |
C | 0 0 + + 0 0 + + |
Assays were performed for the presence of 8 different human
enzymes (E1-E8) in each of the 3 cell lines. These were the
results:
Enzyme Activity | |
E1 E2 E3 E4 E5 E6 E7 E8 | |
Cell Line | |
A | + 0 + + 0 + 0 0 |
B | + 0 0 + + 0 + + |
C | + + + 0 0 + 0 + |
Identify the human chromosome that carries the gene for each
enzyme.
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