Question: The figure below shows the regulation of genes involved in
muscle commitment and differentiation….
The figure below shows the regulation of genes involved in
muscle commitment and differentiation. MyoD, E12/47, Id, and RP58
are transcription factors; MyHC is a protein of the muscle
fiber.
a) Which one of the TFs could be considered both an activator
and a repressor? Explain briefly.
b) What type of binding is represented by the MyoD/E12-47
heterodimer?
c) MyoD and Id proteins share a similar protein domain. Would it
be a DNA binding domain or a protein interaction domain? Be very
specific and justify your answer briefly.
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