Question: The PTEN protein was further analyzed by creating proteins
corresponding to either only the NH2-t…
The PTEN protein was further analyzed by creating proteins
corresponding to either only the NH2-terminal (N in figure) or
central region (C2 in figure) of the protein. These two , as well
as the complete PTEN protein (FL in figure) were tagged with His-Ni
and used in coIP assays with purified histone H1. The results are
presented at right. Which of the two segments of the PTEN protein
interacts with Histone H1? Explain the relevant part of the figure
to justify your answer.
Show transcribed image text 186 352 403 C2 Tal His-PTEN N C2 FL H1
186 352 403 C2 Tal His-PTEN N C2 FL H1