Question: The synthesis of alkylamines by direct substitution from simple alkyl halides and ammonia is usua…
Show transcribed image text The synthesis of alkylamines by direct substitution from simple alkyl halides and ammonia is usually complicated by overalkylation However, this method is much more useful for the preparation of alpha-amino acids from the corresponding alpha -halo acids. Why is overalkylation not a significant problem in the preparation of alpha -amino acids? SmallCircle Amino acids are usually solids and will crystallize as they are formed. Their insolubility effectively limits their reactivity. SmallCircle The product of ammonia addition to the
The synthesis of alkylamines by direct substitution from simple alkyl halides and ammonia is usually complicated by overalkylation However, this method is much more useful for the preparation of alpha-amino acids from the corresponding alpha -halo acids. Why is overalkylation not a significant problem in the preparation of alpha -amino acids? SmallCircle Amino acids are usually solids and will crystallize as they are formed. Their insolubility effectively limits their reactivity. SmallCircle The product of ammonia addition to the
