Question: Three contrasting traits are being studied in C. elegans:
long length (lon-) versus wild-type len…




Three contrasting traits are being studied in C. elegans:
long length (lon-) versus wild-type length (lon+), uncoordinated
movement (unc-) versus wild-type movement (unc+), and blistered
cuticle (bli-) versus normal cuticle (bli+). Each mutant allele is
recessive to the wild-type allele for these three traits. A cross
between females heterozygous at these three loci and wild-type
males yields progeny having the following genotypes:


wild-type females 1010 wild-type males 30 bli- males 32 unc-
males 441 lon- bli- males 430 lon- unc- males 27 unc- bli- males 1
lon- unc- bli- males 39




a. Are the three genes linked? From the given data is it
possible to determine on which chromosome they are located?
b. For the data above, draw the relevant chromosomes in the
heterozygous parent, showing the arrangement of the
alleles.


c. For the data above, calculate the map distances between
the genes. Draw a map showing the linkage relationships and
distances for the three loci.
d. Is there interference? Calculate the coefficient of coincidence
and use it to quantify interference.

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