Question: Which of the following is one example by which cancer cells (or tumors) can promote their own con…

Which of the following is one example by which cancer cells (or
tumors) can promote their own continual proliferation?
Select any/all examples that apply.

A. Tumor cells signal surrounding stromal cells to release
growth factors.

B. Cancer cells constitutively activate signaling pathways that
lie downstream of growth factor receptors.

C. Cancer cells chronically stimulate the intrinsic apoptosis
pathway.

D. Tumors encourage necrotic cell death so as to decrease
pro-inflammatory signals.

E. Cancer cells decrease the expression levels of PTEN.