With regards to pharmacodynamics, answer the followingquestions:
K. Describe how oral vs IV administration of a drug would affectthe quantal dose-response plots (i.e., ED50 and TD50) as well asthe therapeutic index and certain safety factor
L. Draw an antagonist concentration-response plot
- For the antagonist alone
- For the antagonist in the presence of a fixed concentration ofa partial agonist
- How would the above plots be altered in a tissue WITH andWITHOUT spare reserve present
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